Eugenics: Science’s Dark Past or Today’s Biotechnology? Mike Buckwalter Senior Seminar Stan Grove November 22nd, 2006 Outline:
I. Introduction Deep within the essence of all things living lies the desire to excel, succeed, and triumph. In the past, Darwin’s principles of natural selection have shaped the dynamics of organism populations. The strongest organisms tend to survive and pass on their traits to offspring while the weak are filtered out. The invisible doctrine for a species to self-improve manifests itself through the interplay of genes in a gene-pool. Genetically, the environment selects fit traits that evolve a species through time. The evolution of Homo sapiens has reached to the present day, and humankind has been endowed with the magnificent gifts of language, rational thought, and sentience. Rapid technological advances have bestowed humans with the ability to pursue a variety of self-improvements. Perhaps the most potent and controversial entity to enter the realm of technology is genetic engineering. With the discovery of the entire sequence of the human genome, humans are now able to tweak and improve on their very own genetic blueprint. However, this fascination with improving the human condition at the genetic level has persisted for many centuries. Extensive ethical debate reigns over the uses of today’s rapidly developing biotechnology. If screening for genetics defects in an unborn child is appropriate, then is selecting the eye-color and sexual orientation of the baby also appropriate? How long has this idea of shaping the face of the human gene pool persisted? A term that defines the process of changing the human gene pool through any means is eugenics. Thesis: Eugenics has long created unethical and immoral social policies, but while scientific knowledge debunks eugenics’ earlier claims, biotechnology is still carrying on its philosophies in a harmful way.
II. Background Information The history of eugenics has a scope that moves far beyond word-meaning. Rather, the very idea of manipulating or improving the human gene pool must have been practiced even before written language. It is likely that “the first eugenist was not the Spartan legislator, but the primitive savage who killed his sickly child” (Blackwell, 1913). Thought of this way, eugenics can be seen to be a broad concept that incorporates many aspects of human behavior throughout the sweep of history. In the days of the Greek and Roman empires, when war was always an imminent event, it seemed necessary to weed out the weak for the better of society. The age of Greek philosophers produced great thinkers such as Plato and Socrates. In his Republic, Plato articulated what he believed to be the best form of society: his republic. Long before the birth of modern genetics, he outlined his opinion on what would conserve the strong and eliminate the weak. He said that “they [men and women who were Guardians of society] will be bred deliberately to produce the best offspring, as though the Guardians were a pack of hunting dogs” (Plato, 360 B.C.). Plato believed that these practices would encourage the propagation of those he said were fit to be a part of his state. These ideas were held by many men who were high in the council at the time. Sparta, a prominent Greek city, practiced selective infanticide. They would leave their babies outside of the city walls shortly after birth. The babies who survived after a few days were salvaged and considered to be worthy or strong (Amos, 1982).
III. Eugenics – A Historical Perspective Within 40 years of Galton’s publications on eugenics, the forces of history were adopting his views, and the views of Plato, in new and radical ways. After devastation in World War I and the great losses that Germany suffered in the Treaty of Versailles, Adolf Hitler rallied the country together in a great surge of morale in the 1930s (BBCOnline, 1998). Once World War II began in 1939, Hitler’s policy of “Ethnic Cleansing” or “Racial Hygiene” took place as he engineered his vision of the Third Reich with the aim to create the Aryan race. Millions of those considered ‘unfit’ by the standards of the German race were shipped off to concentration camps for extermination: Jews and many other minority groups. A top SS doctor at Auschwitz, Joseph Mengele, performed brutal “scientific” experiments on live subjects in order to test his genetic theories (Posner and Ware, 1986). The Nazi party forcibly sterilized hundreds of thousands of people believed to be ‘unfit’ during the 1930s and 1940s; 400,000 between 1934 and 1937 alone (Yad, 2005).
IV. World War II and Post World War II Eugenics At the turn of the 20th century, the United States was beginning to adopt eugenics policies as well. Beginning in 1896 in Connecticut and then spreading to other states, marriage laws passed legislation that prevented the marrying of the “feeble-minded”, those considered imbeciles, and imbeciles (Kevles, 1985). Following this, the idea that traits such as mental-illness, schizophrenia, and imbecility could run in families became very popular among researchers, just as Galton had proposed decades earlier. The Supreme Court passed laws in 1927 that not only prohibited marriages of unfit people, but forced the sterilization of the mentally ill to prevent that “trait” from being passed to future generations (Lombardo, 2006). Over 45,000 mentally ill individuals had been forcibly sterilized in the United States by the end of World War II (Kevles, 1985). As it can be seen, the principles of eugenics laid out by early proponents were once again being manifested in harmful ways. In California, where the most sterilization was taking place, biologist Paul Popenoe published the results in a book. This book was extensively used by the Nazi government, and they even cited it as a major source during the post World War II Nuremberg trials (Black, 2003). Most non-Catholic nations other than the United States and Germany practiced social policies of eugenics during the first half of the 20th century. Tens of thousands of people were forcibly sterilized and prohibited to marry. By the end of the 1930s, due to Nazi stigma, eugenics had lost much of its political backing (Wikipedia:Eugenics, 2006). Though many eugenics policies remained effective even until the 1970s, advancing science and improved ethical consideration managed to oust eugenics from the scientific community.
V. Modern Eugenics Since the turn of the 21st century, the world has been wrestling with the use of new genetic technologies, while some nations race to be the first to clone a human being. Much attention has been focused on the country of China, where maternity and infant health laws have been criticized as being eugenic (Renzong, 1999). The Chinese people, under considerable pressure from living in a crowded and rapidly-growing nation, enacted a one-child policy in 1978. Because of this, there is pressure to have male offspring (to carry on the family name) and to keep birth defects at a minimum. There may be truth to the criticism; in 1993, a law was passed that intended to "avoid new births of inferior quality and heighten the standards of the whole population” (Fernandes, 1994). Rigorous physical examinations were imposed on married couples to determine proper ‘fitness’ before procreation. In close to 30 years, the policy has prevented an estimated 300 million births, keeping the birth-rate very low (Huiting, 2002). Doctors advise couples who are at risk of producing defective offspring to refrain from marriage or reproduction. However, the ultimate decision is left to the adults. Handicapped people do live in disproportionate poverty, and the Chinese government has come close to passing legislation that would ban couples from having children with defects. However, such laws have not been passed. It can be seen that, while China is receptive to issues of imperfect birth, their society does not condone the wide-spread practice of eugenics in any form. Limiting families to one child may aim to control population growth, but does not aim to improve or alter the human gene pool in any way. Isolated practices of infanticide of female babies and forced sterilization of ‘imbeciles’ do occur, but are not a representation of the whole (Oster, 2005). Population control of a similar kind exists in the form of abortion, a topic of intense controversy in the United States. A controversial book, “Freakonomics,” written by Steven Levitt, proposes the idea that eugenics is being practiced currently in the United States unintentionally through abortion (Levitt, 2005). He cites solid evidence that decreased crime rates in the 1990s correlated with increased abortion rates. From this, he argues that the types of people who have abortions are usually lower-class citizens who tend to make poorer life-choices. By having abortions, these people spare the U.S. many potential criminals (Wikipedia:Eugenics, 2006). Another de facto, yet unintentional source of eugenic practice in the U.S. is the alleged low birth-rates among intelligent women. Advocates of this theory suggest that intelligent women (with privilege and money) tend to postpone or even forsake childbirth in order to pursue higher education. Thus, those genes become underrepresented as women possessing less intelligence tend to give birth more frequently (Sailer, 2005). Abortion and the postponement of childbirth are certainly possible de facto sources of eugenics in the U.S., but there are many medical procedures available to those who wish to give their children greater privilege in the world. In the mid-1990s, a survey of 3,000 geneticists in 37 countries revealed that the overwhelming believe among them is that “eugenics is alive and well” (King, 2000). Genetic counselors across the U.S. confirm that they do not place pressure on parents to make any decisions about their children. However, societal pressures against disability and negative phenotypes implicitly engineer eugenic outcomes in the end. While a genetic counselor may be aware of this and have the capacity to discourage eugenic mentalities, the overriding tenets of American culture will always promote eugenic decisions. Why should parents want anything but the best for their children? It is firmly ingrained into American culture to be the best, and parents reasonably wish for the best in their children. Thus, with the inception of genetic screening and pre-natal testing, the flood-gates have been opened on the ethics of birthing healthy babies. Pre-natal screening has become a powerful tool for pregnant mothers. While the process benefits parents by warning them of any medical pathology present in their unborn child, it also presents an ethical dilemma. Many believe that it is unfair to society to birth a child once a genetic defect is known. In addition to this, 30% of interviewed genetics counselors admitted that they would give a parent negatively-slanted counseling once a defect is detected (King, 2000). Data from many other nations, such as China and India, confirms that a pervading believe about genetics counseling is that it exists to reduce the number of deleterious genes in a population. The very existence of genetics counseling in the first place confirms that the ideology of fit genes still exists. This laissez faire ideology has an outlet, which is genetics counseling.
VI. Today’s Eugenics – Biotechnology Misused? What determines exactly which human traits are genetic and which are not? Imbecility is certainly not a genetic trait, though science was used to engineer its eradication (Wikipedia:Eugenics, 2006). Many diseases are still being studied, and until the exact causes of the diseases are identified, humans have no right to declare the destruction of a gene they do not know. According to the Hardey-Weinberg hypothesis, genotypic frequencies of an allele at a population’s equilibrium will follow expected patterns. For example, Tay-Sachs disease, a fatal condition in infants, is a genetic disease that causes brain degeneration due to the build up of a fatty-acid derivative (ganglioside) in the brain. The disease is an autosomal recessive disease and is found in much higher frequencies in Jewish populations than in the normal population of America (“Tay-Sachs”, 2004). According to Hardy-Weinberg principles, a population’s genome is in a healthy state when there are proper conditions such as random mating and migration in and out. However, in closed populations such as the Jewish and the Amish, the odds of bringing deleterious genes together increase greatly. As a result, autosomal recessive diseases proliferate in much higher frequencies, and these conditions are more commonly seen.
VII. Conclusion
History and science have long been intertwined. The millions of people who have been sterilized or killed in the name of a better gene pool are unfortunate victims of bad science. Most would agree that eugenic actions during the first half of the 20th century were immoral, but they are blind to the undeniable practices that go on today. Pre-natal embryo screening, genetic counseling, and gene-therapy are all modern eugenic practices today. Science is a gift that can be used to heal and relieve suffering, but careful thought must be given to its uses before more people are tossed aside and labeled “imperfect”.
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